Agent Handlers Agent Handlers route communication between agents and your McAfee ePO server. Each McAfee ePO server contains a master Agent Handler. Additional Agent Handlers can be installed on systems throughout your network. Setting up more Agent Handlers provides the following benefits. Helps manage an increased number of products and systems managed by a single, logical McAfee ePO server in situations where the CPU on the database server is not overloaded. Provides fault tolerant and load-balanced communication with many agents, including geographically distributed agents.