Overview McAfee® Endpoint Security for Mac is a comprehensive security solution that protects your Apple Macintosh endpoints and minimizes the risk of exposure to threats. You can use the software on standalone and managed Mac systems. For a standalone Mac — You or your Mac administrator can install the software and configure settings using the interface. For a managed Mac — You can use McAfee® ePolicy Orchestrator® (McAfee® ePO™) or McAfee® ePolicy Orchestrator® Cloud (McAfee ePO™ Cloud) to create, manage, and enforce security policies. You can use the queries and dashboards options to track detections, activities, and status of your managed Mac systems.